Key Ingredients Research
ZINC
Low levels of zinc have been linked to acne, and in a meta-analysis of 25 studies exploring the link between acne vulgaris and zinc levels, zinc supplementation led to a significant reduction in the average number of papules.1 Further research highlighting zinc’s efficacy in combating acne revealed that a mild deficiency in zinc can compromise the immune system and demonstrated that zinc supplementation positively impacts marker expression associated with innate immunity.
The bioavailability of zinc monomethionine has been proven to be better than existing zinc preparations.3 In a study using methionine- bound zinc over a 4-week period, researchers saw a reduction in inflammatory lesions and hypothesized an antibacterial role through the inhibition of the growth of P. acnes bacteria.
PROBIOTIC GUT-SKIN AXIS BLEND
In a 12-week clinical trial in which participants received L. rhamnosus SP1 while the placebo group was given a probiotic-free liquid, the probiotic group exhibited a reduction in acne.6 In further research, patients received a probiotic mixture containing B. lactis, and the results revealed an increase in the levels of anti-inflammatory marker IL-10 following treatment.
In a clinical study on gut health, in which participants were provided probiotic enriched food over 12-weeks, the findings suggest that daily consumption of probiotic strains L. rhamnosus IMC501 and L. paracasei IMC502 supports intestinal microbiota and improves bowel habits.
NIACIN (AS NIACINAMIDE)
Clinical studies have shown that Niacinamide can improve skin health when consumed orally, reducing the frequency and duration of acne flare ups.
VITAMIN C
A comprehensive clinical review investigated the impact of vitamin C on collagen and elastin synthesis. A clinical study’s finding indicated that vitamin C exposure increased collagen levels and stabilized collagen.
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